Supplemental Methodological Studies (SMS) are focused studies that occur during the Vanguard (pilot) phase of the National Children’s Study. SMS are designed to inform the Main Study by addressing the feasibility, acceptability, and cost of items pertaining to methodological, logistical, and operational elements of the Study, such as recruitment and assessment of Study visit instruments.
SMS are initiated and developed from outside the Study protocol planning process and are funded externally. Requests for just data are not considered SMS; SMS involve interaction with Vanguard phase participants and/or requests for Vanguard phase biospecimens or environmental samples (in addition to requests for data). Detailed information and an application are provided here.