Applicants are responsible for developing all informed consent forms and materials required for the conduct of their Supplemental Methodological Study (SMS). Applicants should review the National Children’s Study general consent form in collaboration with the local IRB(s), and determine whether the research proposed in the SMS is covered by the National Children’s Study general consent or whether it requires additional consent forms and materials or waivers of informed consent or documentation of informed consent. The general consent form can be obtained upon request from the National Children’s Study Program Office at: NCS_IRBs@mail.nih.gov.